Shandong Sino Pharmaceutical Technology Co., Ltd.
We are professional supplier of Skin Rejuvenation products,Skin whitening products,Weight Less products,Health care products,Antibiotic,Analgesic,Anti-inflammatory,Vitamin,Health care products,Peptide
Business Type:Trader
Country/Region:China
Ddu Verified
HOT Rank
1. Action
Anti-emetic: Blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ), preventing nausea/vomiting.
Prokinetic: Enhances gastric emptying by stimulating upper GI motility.
2. Indications
Postoperative/chemotherapy-induced nausea & vomiting
Gastroparesis (e.g., diabetic)
GERD (severe reflux unresponsive to other therapy)
| Population | Dosage | |
|---|---|---|
| Adults | 10mg IV/IM every 6-8h (max 30mg/day) | |
| Children | 0.1-0.15mg/kg/dose (max 10mg) | |
| Elderly | Reduce dose by 50% |
Administration Notes:
IV push: Dilute & inject slowly over 1-2min (rapid injection may cause hypotension).
IM: Deep injection into large muscle.
4. Contraindications
GI obstruction/perforation (stimulates motility)
Pheochromocytoma (risk of hypertensive crisis)
Epilepsy/Parkinson's disease (lowers seizure threshold)
5. Adverse Effects
Common: Restlessness, drowsiness, diarrhea
Serious: Tardive dyskinesia (with long-term use), neuroleptic malignant syndrome.
6. Drug Interactions
CNS depressants (e.g., opioids): ↑ Sedation risk.
Serotonergic drugs: ↑ Serotonin syndrome risk.
7. Storage Conditions
Unopened: Below 25°C, protect from light.
Opened vials: Discard immediately (single-use only).
Do not freeze (causes precipitation).
