Shandong Sino Pharmaceutical Technology Co., Ltd.

Water for Injection (WFI) is a highly purified water that meets stringent standards, such as those outlined in the Chinese Pharmacopoeia. It is primarily used for dissolving and diluting active pharmaceutical ingredients to prepare injectable solutions and powders for injection. WFI ensures that the final product is free from impurities and contaminants that could cause adverse reactions in patients. Additionally, WFI is crucial for cleaning and sterilizing medical devices. Surgical instruments and infusion equipment must be thoroughly cleaned with WFI to remove any residues before undergoing high-temperature or chemical sterilization processes. This ensures that the devices are free from microbial contamination and safe for use in medical procedures. WFI may also be used in other medical applications, such as preparing solutions for endoscopic procedures or dialysis fluids, where the purity of water is critical to avoid interference with the diagnostic or therapeutic process.

Dosage and UsageThe dosage and usage of Water for Injection depend on the specific application and the requirements of the pharmaceutical preparation or medical procedure. Here are some general guidelines:

1. Preparation of Injectable Solutions: The volume of WFI used will depend on the concentration of the active ingredient and the desired final volume of the injectable solution. For example, if a drug requires a concentration of 10 mg/mL and the total volume needed is 100 mL, the amount of WFI required will be calculated based on the solubility and concentration requirements of the drug.
2. Cleaning Medical Devices: The amount of WFI used for cleaning will depend on the size and complexity of the medical device. Typically, sufficient WFI is used to ensure that all surfaces are thoroughly rinsed and any residues are removed. This may involve multiple rinses with WFI to ensure complete cleaning.
3. Other Medical Applications: In applications such as endoscopy or dialysis, the volume of WFI used will be determined by the specific protocol of the procedure. For example, in dialysis, the volume of WFI used to prepare the dialysis fluid will be based on the patient's requirements and the specifications of the dialysis machine.

It is important to note that WFI should always be used in accordance with the guidelines provided by the relevant regulatory authorities and the specific requirements of the pharmaceutical or medical procedure. Healthcare professionals and pharmacists should refer to the appropriate guidelines and protocols to ensure the correct usage of WFI.StorageProper storage of Water for Injection is essential to maintain its quality and ensure its suitability for use in medical and pharmaceutical applications. Here are some key storage considerations:

1. Sterile Conditions: WFI must be stored in a sterile environment to prevent microbial contamination. This typically involves using sterile containers and maintaining aseptic handling practices.
2. Temperature Control: WFI should be stored at a controlled temperature, usually between 20°C and 25°C, unless otherwise specified. Temperature control helps to maintain the stability and quality of the water.
3. Protection from Light: WFI should be protected from direct sunlight and stored in a dark place to prevent any potential degradation or contamination.
4. Expiration Date: WFI has an expiration date, and it should be used within this timeframe. Expired WFI should not be used for medical or pharmaceutical purposes.
5. Sealed Containers: WFI should be stored in tightly sealed containers to prevent contamination from the environment. This helps to maintain the water's purity and prevent the ingress of microorganisms or other contaminants.