Shandong Sino Pharmaceutical Technology Co., Ltd.

Product Overview:

The Tetanus Antitoxin 1500IU/0.75ml, derived from equine sources, is a high-quality solution for the prevention and treatment of tetanus. It is designed to neutralize tetanus toxins effectively, providing immediate protection against this potentially life-threatening condition. Trusted by healthcare providers globally, this product ensures safety and reliability in emergency and routine medical settings.
Key Features:
   •     Potency: 1500IU per 0.75ml
   •     Source: Equine-based antitoxin for enhanced effectiveness
   •     Usage: Preventive and therapeutic application for tetanus

 

Active Ingredient	Tetanus Antitoxin
Dosage Form	Injection iv/im
Strength	1500IU per 0.75ml
Manufacturer	Sinopharmatech Co., Ltd.

Mechanism of ActionTetanus antitoxin is used to neutralize unbound tetanus toxin, which is produced by Clostridium tetani. This toxin causes tetanus by interfering with the release of inhibitory neurotransmitters, leading to muscle rigidity and spasms. The antitoxin works by binding to the toxin and preventing it from binding to nerve cells, thereby neutralizing its effects.Dosage Instructions

• Human Tetanus Immune Globulin (HTIG): The preferred antitoxin is HTIG. The Centers for Disease Control and Prevention (CDC) recommends a single intramuscular (IM) dose of 500 units. This dose should be administered as soon as tetanus is suspected, with part of the dose infiltrated around the wound. HTIG should be given at a different site from tetanus toxoid.
• Equine Antitoxin: If HTIG is unavailable, equine antitoxin can be used as an alternative. An intradermal test dose of 0.1 mL in a 1:10 dilution should be administered first to check for hypersensitivity reactions.

Storage ConditionsTetanus antitoxin should be stored according to the manufacturer's instructions. Generally, it should be kept refrigerated at 2°C to 8°C (36°F to 46°F) to maintain its potency and stability. Avoid freezing, as this may damage the product.